Tottenham manager Juande Ramos has been given a favourable draw in his quest for a third successive UEFA Cup triumph.
In the last 32 Spurs will face Slavia Prague, the Czech Republic side already thrashed 7-0 by north London rivals Arsenal in the Champions' League group stage before finishing third to claim a UEFA Cup place.
Slavia was also beaten 4-2 in October by a Sevilla side coached by Ramos when he was still in charge of the Spanish club that he led to UEFA Cup glory in the past two seasons.
Two British sides drew glamour ties, as Bolton was paired with a star-studded Atletico Madrid team and Aberdeen drew Bayern Munich in a rematch of the Cup Winners' Cup quarter-final of 1983 when the Dons went on to take the trophy.
Everton will be confident of defeating SK Brann of Norway while Scottish Premier League leaders Rangers face an awkward tie against Greek side Panathinaikos.
Spurs will be even more confident of making progress having also beaten Slavia 1-0 home and away in the first round of last year's UEFA Cup
But Damien Comolli, director of football at White Hart Lane, said: "At home they are difficult to play and one should not forget they drew at home against Arsenal."
He admitted, however, that the UEFA Cup plays a big part in the club's plans even while the team flirt with the Barclays Premier League relegation zone.
Comolli said: "It is becoming an obsession at the club to be in Europe every year which is a very good obsession. It is a very important competition for us and we are really pleased to be in it at this stage."
"Juande Ramos is a winner and he wants to be in Europe. While we are there he wants to do very well because he is used to winning trophies at the end of the season."
It is 25 years since Sir Alex Ferguson won his first European trophy - the now-defunct Cup Winners' Cup with Aberdeen after beating Bayern Munich 3-2 in the quarter-finals.
Jimmy Calderwood has been presented with a similar challenge in even more daunting circumstances for his side.
Aberdeen has not survived into the new year of a European campaign since 1986 and must now take on a rejuvenated Bayern side which leads the Bundesliga.
Karl Hopfner, Bayern Munich executive director, said: "There is a lot of history for us and we say hello again to Aberdeen 25 years later."
"It was a 0-0 draw in Munich in the first leg and that was one of the best games by a British team in the old Olympic Stadium."
"We are having a good season, the same points as Werder Bremen with better goal difference, because the new players who came in the summer - the French international Franck Ribery and Luca Toni from Italy - have done very well."
Toni is sure of a warm welcome at Pittodrie after his three goals against Scotland in Euro 2008 qualifying sent Italy through at the Scots' expense.
Aberdeen was outclassed 2-0 by Atletico Madrid in the group phase and the Spaniards - featuring former Premier League stars Jose Antonio Reyes, Diego Forlan and Luis Garcia - will travel to the Reebok Stadium to face Bolton in the first leg of their last 32 tie.
Everton was one of only two clubs to win all four group